CVS Pharmacy is closing hundreds of stores in 2025 as part of restructuring efforts.
According to its recent annual report from February 2025, CVS announced will close 271 retail pharmacies this year.
This announcement followed the retail pharmacy chain’s closure of 900 locations between 2022 and 2024.
READ MORE: Rite Aid closings 2025 – See the full list of stores shutting down
Here’s why CVS is closing so many locations in 2025.
Why is CVS closing pharmacy locations in 2025?
The CVS 2024 annual report said CVS decided to close pharmacy locations in 2025 as part of its “enterprise-wide restructuring plan intended to streamline and simplify the organization.”
A spokesperson confirmed to Newsweek that the pharmacy closures would be a way to optimize “existing stores and pharmacies.” They added that the recent closures were based on shifting consumer trends and not industry pressures.
Which CVS stores are closing?
While CVS has not released a specific list of stores that are closing, news outlets, such as Newsweek, and consumer trends websites, like The Krazy Coupon Lady, have compiled lists of stores that have closed or are about to close this year.
The following stores are closing or have already closed in 2025:
Alabama
- 2901 Morgan Rd., Bessemer
- 3303 Clairmont Ave., Birmingham
California
- 499 Haight St., San Francisco
- 1701 K St., Sacramento
Florida
- 3090 S. Monroe St., Tallahassee
- 13300 E. Colonial Dr., Orlando
- 2201 Edgewater Dr., Orlando
Georgia
- 439 Highland Blvd., Atlanta
Indiana
- 9550 Allisonville Rd., Indianapolis
Illinois
- 8639 S. Cicero Ave., Chicago
- 401 W. Armitage Ave., Chicago
- 2000 Skokie Valley Rd., Highland Park
Iowa
- 2420 Lincoln Way, Ames
- 215 Euclid Ave., Des Moines
Maryland
- 1000 S. Charles St., Federal Hill, Baltimore
- 7235 Wisconsin Ave., Bethesda
- 34 N. Cannon Ave., Hagerstown
Massachusetts
- 55 Summer St., Boston
Michigan
- 28774 Gratiot Ave., Roseville
- 27700 Harper Ave., St. Clair Shores
Missouri
- 2435 Independence Ave., Kansas City
- 9433 Manchester Rd., Saint Louis
- 4531 Troost Ave., Kansas City
New York
- 955 Payne Ave., North Tonawanda
- 153 Central Ave., Albany
- 1026 Madison Ave., Albany
- 1241 Lexington Ave., New York
- 1654 Richmond Ave., Staten Island
North Carolina
- 201 W. 4th St., Winston-Salem
Ohio
- 10825 Kinsman Rd., Cleveland
Pennsylvania
- 125 E. Main St., Plymouth
Texas
- 3890 Phelan Blvd., Beaumont
Virginia
- 10390 Willard Way, Fairfax
Washington, D.C.
- 1117 10th St. NW
- 1100 4th St. SW
- 400 Massachusetts Ave. NW
- 1515 New York Ave. NE
- 4500 Wisconsin Ave. NW
- 7828 Georgia Ave. NW
More Major Store Closing News
- Rite Aid is closing over 100 more locations nationwide, including in N.J. Is your store affected?
- Home decor retailer abruptly files for bankruptcy, closing 26 stores nationwide
- Fried chicken chain is teetering on Chapter 7 bankruptcy, if a sale is not approved
- Rite Aid closings 2025: See the full list of stores shutting down
- Major U.S. restaurant chain to close up to 21 locations in 2025
Our journalism needs your support. Please subscribe today to NJ.com.
Katherine Rodriguez can be reached at krodriguez@njadvancemedia.com. Have a tip? Tell us at nj.com/tips.
